| Mycobacteria - Mycobacterium leprae, Mycobacterium chelonae, Mycobacterium fortuitum, Mycobacterium kansasii, complex Mycobacterium avium, which includes Mycobacterium avium i Mycobacterium intracellulare;
Biaxin tablets
other microorganisms - Mycoplasma pneumoniae, Chlamydia pneumoniae (trachomatis).
Production of beta-lactamase does not affect the activity of the drug.
Pharmacokinetics. After oral clarithromycin is rapidly absorbed, reaching maximum concentration after 2 hours. The biological availability of about 68%. After absorption of the drug penetrates into most tissues, except the central nervous system. Since the protein binds 80% of the drug.
Biaxin tablets
Metabolized by the liver to form the main metabolite 14-hidroksyklarytromitsynu having the same or one to two orders of magnitude less (depending on the type of microorganism) antimicrobial activity than unmodified material. Excreted in urine 36% of the dose in the feces - 52%. The half-life is dose-dependent.
Pharmaceutical characteristics.
Basic physical and chemical properties
biconvex oval blue pills coated with a notch on one side.
Expiration date
3 years.
Storage conditions
Store in a dark place at a temperature below 25 ° C. Keep out of reach of children
Biaxin tablets
Tablets 250 mg number 7 in the blister, 2 blisters in a box;
500 mg number 7 in the blister, 1 blister in a box.
supply:
Prescription.
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