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When concomitantly increases the concentration in the blood of drugs metabolized in the liver via the P450 cytochrome enzymes, anticoagulants, carbamazepine, theophylline, astemizole, cisapride, terfenadine (2-3 times), triazolam, midazolam, cyclosporine, disopyramide, phenytoin, rifabutin, lovastatin, digoxin, ergot alkaloids, and others.
Reduces absorption of zidovudine (between taking drugs should be an interval of at least 4 hours).
Perhaps the development of cross-resistance between clarithromycin, lincomycin and clindamycin.
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Inside, adults and children over 12 years - 250-500 mg 2 times a day. Duration of treatment - 6-14 days.
In severe infections, or in the case of oral administration in the form prescribed difficulties in / injection at a dose of 500 mg / day for 2-5 days, with further transfer to the oral administration of 500 mg / day. The total duration of treatment is 10 days.
In the treatment of infections caused by Mycobacterium avium, sinusitis and severe infections (including those caused by Haemophilus influenzae) administered by mouth, 0.5-1 g of 2 times a day (maximum - 2 g). Duration of treatment - 6 months or more.
In patients with chronic renal failure (Cl creatinine less than 30 ml / min or serum creatinine concentration of 3.3 mg / 100 ml) - 250 mg / day (once), in severe infections - 250 mg 2 times a day. The maximum duration of treatment in this patient group - 14 days.
Buy clarithromycin 500mg tablets
Symptoms: impaired function of the gastrointestinal tract, headache, confusion.
Treatment: gastric lavage, symptomatic therapy.
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