Clarithromycin 500mg tablets price
| It is necessary to consider the possibility of cross resistance between clarithromycin and other macrolide drugs and a number of lincomycin and clindamycin.Clarithromycin 500mg tablets price
Ritonavir increases the value of AUC (area under the curve "concentration / time") of clarithromycin during their concomitant use. No need to change the dose of clarithromycin-Kredofarm patients with normal renal function. In patients with renal impairment with creatinine clearance 30-60 ml / min the dose of clarithromycin-Kredofarm should be reduced by 50%, while the value of creatinine clearance less than 30 ml / min - 75%. Dose-Kredofarm clarithromycin> 1 g / day should not be administered concurrently with ritonavir. Clarithromycin 500mg tablets price
Concomitant use of clarithromycin tablets and zidovudine-Kredofarm HIV-infected patients may lower constant zidovudine levels. However, this interaction was not observed in HIV-infected children with concomitant use of clarithromycin-Kredofarm, suspension of zidovudine or dydeoksynozynom.
Pharmacological properties
Pharmacodynamics. Clarithromycin - macrolide antibiotics, semi-synthetic derivative of erythromycin. The modified structure of the molecule makes the drug more bioavailable and stable in the acidic environment increases the concentration in the tissues, antimicrobial spectrum expands, extends the half-life that allows you to administer the drug twice a day and thus improve the treatment of patients. The drug inhibits a microbial cell protein synthesis by interacting with the 50S ribosomal subunit of bacteria. Clarithromycin 500mg tablets price
Clarithromycin-Kredofarm detects most active against most strains of the following microorganisms:
aerobic gram - Staphylococcus aureus, Streptococcus agalactiae (pyogenes, viridans, pneumoniae), Listeria monocytogenes; aerobic gram - Haemophilus influenzae (parainfluenzae), Neisseria gonorrhoeae, Helicobacter pylori, Legionella pneumophila, Moraxella (Branhamella) catarrhalis;
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