| Imodium is an antidiarrheal drug symptomatic.
Structure, Composition and Packaging
Producing Imodium several dosage forms:
In the form of tablets for sucking, lyophilized, round, white, or almost white.
Active substance: 1 tablet - 2 mg of loperamide hydrochloride.
Auxiliary components: mint flavor, aspartame, mannitol, gelatin, sodium hydrogen carbonate.Cheap imodium
The carton pack - 1 to 6 blister, 10 tablets each.
The carton pack - 2 blisters of 10 tablets each.
In capsule form, size №4, gelatin, hard, green cap with the inscription white "Imodium", the body is dark gray with a white inscription "JANSSEN".
Active substance: 1 capsule - 2 mg of loperamide hydrochloride.
Auxiliary ingredients: corn starch, talc, lactose monohydrate, magnesium stearate.
The capsule - white powder.
capsule shell: yellow iron oxide, sodium erythrosine, gelatin, black iron oxide, sodium indigotindisulfonat, titanium dioxide.
Cheap imodium
The active agent in the gut wall binding to opioid receptors and inhibits acetylcholine release of prostaglandins, which leads to a reduction of time and increased peristalsis movement through the bowel contents. It tends considerably to increase the tone of the anal sphincter, thereby reducing the urge to defecate and fecal incontinence.
Pharmacokinetics
Cheap imodium
Absorption after administration of loperamide - 40%.
Distribution
With plasma proteins svyazyvanie- about 95%, mainly to albumin.
Metabolism
Oxidative N-demethylation of an intensive metabolism in liver by the first movement.
breeding
T1 / 2- fixed 10.8 parts (9 to 14 hours). Mainly excreted in the feces. The insignificant part of the output through the urine in the form of conjugated metabolites.
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