| Biaxin 500 mg price
Clarithromycin rapidly and well absorbed from the gastrointestinal tract after oral administration of the drug in tablet form. Microbiologically active metabolite 14-hidroksyklarytromitsyn formed by first-pass metabolism. Clarithromycin can be used regardless of the meal because the food does not affect the bioavailability of clarithromycin tablets. Food slightly delays the start of absorption of clarithromycin and formation of the 14-hidroksymetabolitu. The pharmacokinetics of clarithromycin nonlinear; but the equilibrium concentration is achieved within 2 days of preparation. When using 250 mg 2 times a day for 15-20% of unchanged drug excreted in the urine. At a dose of 500 mg 2 times daily output of urine drug intensively (approximately 36%). 14 hidroksyklarytromitsyn is the main metabolites excreted in the urine in an amount of 10-15% of the applied dose. Most of the remaining dose excreted in the faeces, mainly with bile. 5-10% of the parent compound is found in the feces.
Biaxin 500 mg price
When using clarithromycin 500 mg 3 times daily concentrations of clarithromycin plasma levels increased compared with a dose of 500 mg 2 times a day.
Clarithromycin concentrations in tissues several times higher than the concentration of drug in the blood. Elevated concentrations were found in tonzylyarniy as well as in lung tissues. Clarithromycin at therapeutic doses is 80% bound to plasma proteins.
Clarithromycin penetrates the gastric mucosa. The content of clarithromycin in the lining of the stomach tissue and higher in the application together with clarithromycin omeprazole than when clarithromycin alone.
The pharmaceutical properties. Basic physical and chemical properties:
dosage of 250 mg: Round biconvex tablets, coated yellow, with a line fault on the one hand;
dosage of 500 mg: oblong shape tablets, coated yellow, with a fault line on one side.
Expiration date
2 years.
Do not use after the expiration date printed on the packaging.
Biaxin 500 mg price
Store in a dry, dark and inaccessible to children at or above 30 ° C.
Packaging
The dosage of 250 mg: 10 tablets in a blister 1 blister in a pack. On 7 tablets in a blister 1 or 2 blisters in a pack.
The dosage of 500 mg, 5 tablets in a blister 1 or 2 blisters in a pack. On 7 tablets in a blister 1 or 2 blisters in a pack.
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