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Overdose
Nausea, vomiting, diarrhea. When applying the dose more than 8 grams of clarithromycin may change in mental status, paranoid behavior, hypokalemia and hypoxemia.
Treatment. It should quickly wash the stomach and prescribe symptomatic therapy.
It is unlikely that hemodialysis or peritoneal dialysis significant impact on levels of clarithromycin in serum, because these treatments are not recommended.
Use during pregnancy and lactation
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During pregnancy and lactation the drug is used only if the expected benefit to the mother outweighs the potential risk to the fetus or child. During lactation the drug should be discontinued.
Children
The drug in this dosage form is not prescribed to children under 10 years.
The application features
Clarithromycin-Kredofarm should be used with caution in patients with impaired liver and / or kidney, and elderly patients.
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Need to be careful when appointing the drug to patients with renal insufficiency of moderate to severe severity. In patients with renal insufficiency (creatinine clearance at least 30 mL / min), the dose should be reduced by 2 times. The maximum duration of treatment in this group of patients should not exceed 14 days.
No need for dose adjustment in patients with hepatic insufficiency of moderate to severe severity, but with normal functioning kidneys.
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