| Contraindications
Cialis is not indicated in patients with known hypersensitivity to tadalafil.
Admission Cialis is contraindicated in patients taking organic nitrates.
Tadalafil is not indicated for women and children under the age of 18 years.
It is not recommended to take the drug Cialis for patients with diseases of the cardiovascular system, in which unwanted sexual activity, including patients with recent myocardial infarction or a stroke as well as suffering from heart failure, a second degree, unstable angina, uncontrolled arrhythmias, or hypertension, severe arterial hypotension.10mg cialis dosage
It should be used with caution in patients with drug Cialis increased risk of priapism, including patients with leukemia, serpopodobno-cell anemia, multiple myeloma, angular curvature of the penis, cavernous fibrosis and Peyronie's disease.
In addition, caution should be exercised by appointing tadalafil to patients with impaired renal function and liver function, and in patients receiving alpha-blockers.
Drug interactions
Prohibited the simultaneous use of organic nitrates with tadalafil.
Tadalafil did not alter the pharmacokinetic profile of drugs metabolized with participation of cytochrome P450.10mg cialis dosage
When combined with the admission of the drug Cialis and CYP3 A4 inhibitors may increase plasma concentrations of tadalafil. In particular should be used with caution tadalafil combined with ketakonazolom, ritonavir, saquinavir, erythromycin and itraconazole.
Perhaps the decline in plasma concentrations of tadalafil in the combined use with inductors CYP3 A4, such as rifampicin.10mg cialis dosage
Cialis is the combined use may potentiate the action of antihypertensive drugs.
Antacids and enveloping means reduce the bioavailability of tadalafil in the combined reception.
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